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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAH All Species: 34.85
Human Site: S23 Identified Species: 69.7
UniProt: P16930 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16930 NP_000128.1 419 46374 S23 N L P Y G V F S T R G D P R P
Chimpanzee Pan troglodytes XP_001155476 421 46561 S23 N L P Y G V F S T R G D P R P
Rhesus Macaque Macaca mulatta XP_001109382 419 46350 S23 N L P Y G V F S T R G D P R L
Dog Lupus familis XP_852646 406 45079 S23 N L P Y G V F S T P G N P R Q
Cat Felis silvestris
Mouse Mus musculus P35505 419 46085 S23 N L P Y G V F S T Q S N P K P
Rat Rattus norvegicus P25093 419 45957 S23 N L P Y G V F S T Q S N P K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_413855 419 46530 S23 N L P Y G V F S T R E E P R H
Frog Xenopus laevis NP_001080458 420 46648 S23 N L P Y G V F S T H D E P R H
Zebra Danio Brachydanio rerio NP_955895 348 38736
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524830 417 46453 S25 N L P Y A V F S T E N N K V H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_509083 418 46026 S24 N L P Y G V F S T K A D S S R
Sea Urchin Strong. purpuratus XP_787535 389 42602 N24 S Q I K D L F N G A I L S E C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 96.9 75.8 N.A. 89 88.5 N.A. N.A. 80.1 74.5 62.5 N.A. 60.3 N.A. 64.4 63
Protein Similarity: 100 99 98 79.7 N.A. 95.2 94.2 N.A. N.A. 89.2 83.8 72.3 N.A. 73.7 N.A. 76.8 75.1
P-Site Identity: 100 100 93.3 80 N.A. 73.3 73.3 N.A. N.A. 80 73.3 0 N.A. 53.3 N.A. 66.6 6.6
P-Site Similarity: 100 100 93.3 86.6 N.A. 93.3 93.3 N.A. N.A. 86.6 80 0 N.A. 60 N.A. 73.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 0 0 0 9 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 0 0 9 0 0 0 0 0 9 34 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 9 9 17 0 9 0 % E
% Phe: 0 0 0 0 0 0 92 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 75 0 0 0 9 0 34 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 25 % H
% Ile: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 0 % I
% Lys: 0 0 0 9 0 0 0 0 0 9 0 0 9 17 0 % K
% Leu: 0 84 0 0 0 9 0 0 0 0 0 9 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 84 0 0 0 0 0 0 9 0 0 9 34 0 0 0 % N
% Pro: 0 0 84 0 0 0 0 0 0 9 0 0 67 0 34 % P
% Gln: 0 9 0 0 0 0 0 0 0 17 0 0 0 0 9 % Q
% Arg: 0 0 0 0 0 0 0 0 0 34 0 0 0 50 9 % R
% Ser: 9 0 0 0 0 0 0 84 0 0 17 0 17 9 0 % S
% Thr: 0 0 0 0 0 0 0 0 84 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 84 0 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 84 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _